Efird, Jimmy T.O’Neal, Wesley T.Davies, Stephen W.Kennedy, Whitney L.Alger, Lada N.O’Neal, Jason B.Ferguson, T. BruceKypson, Alan P.2014-04-112013Efird, Jimmy T., Wesley T. O’Neal, Stephen W. Davies, Whitney L. Kennedy, Lada N. Alger, Jason B. O’Neal, T. Bruce Ferguson, and Alan P. Kypson. 2013. “Long-Term Mortality of 306,868 Patients with Multi-Vessel Coronary Artery Disease: CABG versus PCI.” British journal of medicine and medical research 3 (4): 1248-1257.2231-0614http://nrs.harvard.edu/urn-3:HUL.InstRepos:12064564Background: Several randomized controlled trials (RCT) have reported no difference in long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). The purpose of this pooled observational analysis was to compare recent retrospective studies examining long-term survival of patients with multi-vessel coronary artery disease undergoing CABG and PCI. Methodology We searched Medline for observational studies comparing long-term (>1 year) survival between CABG and PCI for the treatment of multi-vessel coronary artery disease over the past 10 years. Results: Eight studies met inclusion criteria. A total of 306,868 patients (155,502 CABG; 151,366 PCI) were identified. Follow-up ranged from 1 to 8 years. Mantel-Haenszel combined hazard ratios (HR) for mortality demonstrated a protective benefit of CABG compared with PCI (HR=0.77, 95%CI=0.75–0.79). Conclusion: These findings suggest a long-term survival advantage for CABG compared with PCI in patients with multi-vessel coronary artery disease.en-USCABGPCIsurvivallong-termJournal Article2014-04-11