Gilbert, Aubrey LJakobiec, Frederick AChodosh, JamesEliott, Dean2014-08-132014Gilbert, Aubrey L, Frederick A Jakobiec, James Chodosh, and Dean Eliott. 2014. “A comparison of retrokeratoprosthetic membrane and conjunctival inflammatory responses to silicone oil.” Journal of Ophthalmic Inflammation and Infection 4 (1): 15. doi:10.1186/s12348-014-0015-y. http://dx.doi.org/10.1186/s12348-014-0015-y.1869-5760http://nrs.harvard.edu/urn-3:HUL.InstRepos:12717607Silicone oil continues to be an important aid in retinal detachment surgery. We report a case in which disparate responses to silicone oil were noted in the conjunctiva and intraocularly. Intraocularly, the oil permeated a fibrous membrane that formed behind a keratoprosthesis, the first example of this phenomenon. We detail the histological response to the oil at this site as well as a distinctly different reaction present to oil in the conjunctiva of the same eye. The divergence of histological responses provides a demonstration of the eye's apparent retained capacity to protect against intraocular inflammation, despite multiple previous surgeries.en-USRetrokeratoprosthetic membraneGranulomatous reactionSilicone oilConjunctivaJournal Article2014-08-1310.1186/s12348-014-0015-y