Robinson, Thomas N.Wu, Daniel S.Sauaia, AngelaDunn, Christina L.Stevens-Lapsley, Jennifer E.Moss, MarcStiegmann, Greg V.Gajdos, CsabaCleveland, Joseph C.Inouye, Sharon2017-08-152013Robinson, Thomas N., Daniel S. Wu, Angela Sauaia, Christina L. Dunn, Jennifer E. Stevens-Lapsley, Marc Moss, Greg V. Stiegmann, Csaba Gajdos, Joseph C. Cleveland, and Sharon K. Inouye. 2013. “Slower Walking Speed Forecasts Increased Postoperative Morbidity and 1-Year Mortality Across Surgical Specialties.” Annals of Surgery: 1. doi:10.1097/sla.0b013e3182a4e96c.0003-4932http://nrs.harvard.edu/urn-3:HUL.InstRepos:33750339Objective The purpose of this study was to determine the relationship between the timed up-and-go test and postoperative morbidity and one-year mortality, and to compare the timed up-and-go to the standard-of-care surgical risk calculators for prediction of postoperative complications. Methods In this prospective cohort study, patients 65 years and older undergoing elective colorectal and cardiac operations with a minimum of one-year follow-up were included. The timed up-and-go test was performed preoperatively. This timed test starts with the subject standing from a chair, walking ten feet, returning to the chair, and ends after the subject sits. Timed up-and-go results were grouped: Fast≤10 sec, Intermediate=11-14 sec, Slow≥15 sec. Receiver operating characteristic curves were used to compare the three timed-up-and-go groups to current standard-of-care surgical risk calculators at forecasting postoperative complications. Results This study included 272 subjects (mean age of 74±6 years). Slower timed up-and-go was associated with an increased postoperative complications following colorectal (fast-13%, intermediate-29% and slow-77%;p<0.001) and cardiac (fast-11%, intermediate-26% and slow-52%;p<0.001) operations. Slower timed up-and-go was associated with increased one-year mortality following both colorectal (fast-3%, intermediate-10% and slow-31%;p=0.006) and cardiac (fast-2%, intermediate-3% and slow-12%;p=0.039) operations. Receiver operating characteristic area under curve of the timed up-and-go and the risk calculators for the colorectal group was 0.775 (95% CI:0.670,0.880) and 0.554 (95% CI:0.499,0.609), and for the cardiac group was 0.684 (95% CI:0.603,0.766) and 0.552 (95% CI:0.477,0.626). Conclusions Slower timed up-and-go forecasted increased postoperative complications and one-year mortality across surgical specialties. Regardless of operation performed, the timed up-and-go compared favorably to the more complex risk calculators at forecasting postoperative complications.en-USJournal Article2014-12-20Robinson TN, Wu DS, Sauaia A, Dunn CL, Stevens-Lapsley JE, Moss M, Steigmann GV, Gajdos C, Cleveland JC, Inouye SK2017-08-1510.1097/SLA.0b013e3182a4e96c