Carere, Deanna AlexisCouper, Mick PCrawford, Scott DKalia, Sarah SDuggan, Jake RMoreno, Tanya AMountain, Joanna LRoberts, J ScottGreen, Robert2015-01-052014Carere, Deanna Alexis, Mick P Couper, Scott D Crawford, Sarah S Kalia, Jake R Duggan, Tanya A Moreno, Joanna L Mountain, J Scott Roberts, and Robert C Green. 2014. “Design, methods, and participant characteristics of the Impact of Personal Genomics (PGen) Study, a prospective cohort study of direct-to-consumer personal genomic testing customers.” Genome Medicine 6 (12): 96. doi:10.1186/s13073-014-0096-0. http://dx.doi.org/10.1186/s13073-014-0096-0.1756-994Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13581153Designed in collaboration with 23andMe and Pathway Genomics, the Impact of Personal Genomics (PGen) Study serves as a model for academic-industry partnership and provides a longitudinal dataset for studying psychosocial, behavioral, and health outcomes related to direct-to-consumer personal genomic testing (PGT). Web-based surveys administered at three time points, and linked to individual-level PGT results, provide data on 1,464 PGT customers, of which 71% completed each follow-up survey and 64% completed all three surveys. The cohort includes 15.7% individuals of non-white ethnicity, and encompasses a range of income, education, and health levels. Over 90% of participants agreed to re-contact for future research. Electronic supplementary material The online version of this article (doi:10.1186/s13073-014-0096-0) contains supplementary material, which is available to authorized users.en-USJournal Article2015-01-0510.1186/s13073-014-0096-0