Vunjak-Novakovic, GordanaBhatia, SangeetaChen, ChristopherHirschi, Karen2015-01-052010Vunjak-Novakovic, Gordana, Sangeeta Bhatia, Christopher Chen, and Karen Hirschi. 2010. “HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease.” Stem Cell Research & Therapy 4 (Suppl 1): S8. doi:10.1186/scrt369. http://dx.doi.org/10.1186/scrt369.1757-6512http://nrs.harvard.edu/urn-3:HUL.InstRepos:13581276Our project team is developing an integrated microphysiological platform with functionally connected vascular, liver and cardiac microtissues derived from a single line of human pluripotent stem cells. The platform enables functional representation of human physiology in conjunction with real-time biological readouts (via imaging and homologous reporters for all three cell phenotypes) and compatibility with high-throughput/high-content analysis. In this paper, we summarize progress made over the first year of the grant.en-USJournal Article2015-01-0510.1186/scrt369