King, G. M.Golovchenko, Jene2016-11-172005King, G. M., and J. A. Golovchenko. 2005. Probing Nanotube-Nanopore Interactions. Physical Review Letters 95, no. 21: 21603-1-216103-4. doi:10.1103/physrevlett.95.216103.0031-9007http://nrs.harvard.edu/urn-3:HUL.InstRepos:29405818We demonstrate a new nanoscale system consisting of a nanotube threaded through a nanopore in aqueous solution. Its electrical and mechanical properties are sensitive to experimentally controllable conformational changes on sub-Angstrom length scales. Ionic current transport through a nanopore is significantly suppressed by the threading nanotube and the mechanical interactions between the nanotube and pore are accounted for by a folding geometry. The experiments provide first measurements of the longitudinal resolution and metrology of a solid-state nanopore “microscope.” This new nanostructure provides a means to study molecule-nanotube interactions in conducting ionic solutions as well as geometrical and surface properties of nanopores and nanotubes.en-USJournal Article2016-11-1710.1103/PhysRevLett.95.216103