Naxerova, KamilaElledge, Stephen2015-08-032015Naxerova, Kamila, and Stephen J Elledge. 2015. “Taking the brakes off telomerase.” eLife 4 (1): e09519. doi:10.7554/eLife.09519. http://dx.doi.org/10.7554/eLife.09519.2050-084Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:17820779Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.en-USInsightOncogenesistelomerase TERTimmortalizationcancer mechanismgenome editingtumor spectrumssociated systems 9 CAS9humanTaking the brakes off telomeraseJournal Article2015-08-0310.7554/eLife.09519