Haugen, JohanneUlak, ManjesworiChandyo, Ram K.Henjum, SigrunThorne-Lyman, Andrew LucianUeland, Per MagneMidtun, ØivindShrestha, Prakash S.Strand, Tor A.2017-02-182016Haugen, Johanne, Manjeswori Ulak, Ram K. Chandyo, Sigrun Henjum, Andrew L. Thorne-Lyman, Per Magne Ueland, Øivind Midtun, Prakash S. Shrestha, and Tor A. Strand. 2016. “Low Prevalence of Vitamin D Insufficiency among Nepalese Infants Despite High Prevalence of Vitamin D Insufficiency among Their Mothers.” Nutrients 8 (12): 825. doi:10.3390/nu8120825. http://dx.doi.org/10.3390/nu8120825.2072-6643http://nrs.harvard.edu/urn-3:HUL.InstRepos:30371117Background: Describing vitamin D status and its predictors in various populations is important in order to target public health measures. Objectives: To describe the status and predictors of vitamin D status in healthy Nepalese mothers and infants. Methods: 500 randomly selected Nepalese mother and infant pairs were included in a cross-sectional study. Plasma 25(OH)D concentrations were measured by LC-MS/MS and multiple linear regression analyses were used to identify predictors of vitamin D status. Results: Among the infants, the prevalence of vitamin D insufficiency (25(OH)D <50 nmol/L) and deficiency (<30 nmol/L) were 3.6% and 0.6%, respectively, in contrast to 59.8% and 14.0% among their mothers. Infant 25(OH)D concentrations were negatively associated with infant age and positively associated with maternal vitamin D status and body mass index (BMI), explaining 22% of the variability in 25(OH)D concentration. Global solar radiation, maternal age and BMI predicted maternal 25(OH)D concentration, explaining 9.7% of its variability. Conclusion: Age and maternal vitamin D status are the main predictors of vitamin D status in infants in Bhaktapur, Nepal, who have adequate vitamin D status despite poor vitamin D status in their mothers.en-US25(OH)Dvitamin D statusseasonlactating mothersinfantsNepalJournal Article2017-02-1810.3390/nu8120825