Gram-Scale Synthesis of the A′B′-Subunit of Angelmicin B

Milgram, Benjamin CharlesLiau, BrianShair, Matthew2017-07-182011Milgram, Benjamin C., Brian B. Liau, and Matthew D. Shair. 2011. “Gram-Scale Synthesis of the A′B′-Subunit of Angelmicin B.” Organic Letters 13 (24) (December 16): 6436–6439. doi:10.1021/ol202728v.1523-7060http://nrs.harvard.edu/urn-3:HUL.InstRepos:33464238A gram-scale enantiospecific synthesis of the A’B’-subunit of angelmicin B is reported. The synthesis involves a Lewis acid-catalyzed contrasteric Diels–Alder reaction and a tandem silyl zincate 1,6-addition/enolate oxidation sequence.en-USGram-Scale Synthesis of the A′B′-Subunit of Angelmicin BJournal Article2017-05-1120112017-07-1810.1021/ol202728v