Moy, MarilynGould, Michael K.Liu, In-Lu AmyLee, Janet S.Nguyen, Huong Q.2016-11-182016Moy, Marilyn L., Michael K. Gould, In-Lu Amy Liu, Janet S. Lee, and Huong Q. Nguyen. 2016. “Physical activity assessed in routine care predicts mortality after a COPD hospitalisation.” ERJ Open Research 2 (1): 00062-2015. doi:10.1183/23120541.00062-2015. http://dx.doi.org/10.1183/23120541.00062-2015.2312-0541http://nrs.harvard.edu/urn-3:HUL.InstRepos:29408180The independent relationship between physical inactivity and risk of death after an index chronic obstructive pulmonary disease (COPD) hospitalisation is unknown. We conducted a retrospective cohort study in a large integrated healthcare system. Patients were included if they were hospitalised for COPD between January 1, 2011 and December 31, 2011. All-cause mortality in the 12 months after discharge was the primary outcome. Physical activity, expressed as self-reported minutes of moderate to vigorous physical activity (MVPA), was routinely assessed at outpatient visits prior to hospitalisation. 1727 (73%) patients were inactive (0 min of MVPA per week), 412 (17%) were insufficiently active (1–149 min of MVPA per week) and 231 (10%) were active (≥150 min of MVPA per week). Adjusted Cox regression models assessed risk of death across the MVPA categories. Among 2370 patients (55% females and mean age 73±11 years), there were 464 (20%) deaths. Patients who were insufficiently active or active had a 28% (adjusted HR 0.72 (95% CI 0.54–0.97), p=0.03) and 47% (adjusted HR 0.53 (95% CI 0.34–0.84), p<0.01) lower risk of death, respectively, in the 12 months following an index COPD hospitalisation compared to inactive patients. Any level of MVPA is associated with lower risk of all-cause mortality after a COPD hospitalisation. Routine assessment of physical activity in clinical care would identify persons at high risk for dying after COPD hospitalisation.en-USJournal Article2016-11-1810.1183/23120541.00062-2015