Zhang, JitaoFiore, AntonioYun, Seok-HyunKim, HanyoupScarcelli, Giuliano2016-11-182016Zhang, Jitao, Antonio Fiore, Seok-Hyun Yun, Hanyoup Kim, and Giuliano Scarcelli. 2016. “Line-scanning Brillouin microscopy for rapid non-invasive mechanical imaging.” Scientific Reports 6 (1): 35398. doi:10.1038/srep35398. http://dx.doi.org/10.1038/srep35398.2045-2322http://nrs.harvard.edu/urn-3:HUL.InstRepos:29408216Brillouin spectroscopy probes the mechanical properties of material by measuring the optical frequency shift induced by photon-phonon scattering interactions. In traditional configurations, Brillouin spectrometers measure only one point of the sample at a time. This results in long acquisition times for mechanical imaging of large areas. In this work, we demonstrate a parallel detection configuration where the Brillouin shift of hundreds of points in a line can be measured simultaneously. In mm-sized samples, this novel configuration effectively shortens the acquisition time of two-dimensional Brillouin imaging from hours to tens of seconds, thus making it a powerful technology for label-free mechanical characterization of tissue and biomaterials.en-USLine-scanning Brillouin microscopy for rapid non-invasive mechanical imagingJournal Article2016-11-1810.1038/srep35398