Morris, Martha ClareTangney, Christy C.Wang, YaminSacks, FrankBennett, David A.Aggarwal, Neelum T.2017-02-072015Morris, Martha Clare, Christy C. Tangney, Yamin Wang, Frank M. Sacks, David A. Bennett, and Neelum T. Aggarwal. 2015. “MIND Diet Associated with Reduced Incidence of Alzheimer’s Disease.” Alzheimer’s & Dementia 11 (9) (September): 1007–1014. doi:10.1016/j.jalz.2014.11.009.1552-5260http://nrs.harvard.edu/urn-3:HUL.InstRepos:30205719INTRODUCTION: In a previous study, higher concordance to the MIND diet, a hybrid Mediterranean-Dietary Approaches to Stop Hypertension diet, was associated with slower cognitive decline. In this study we related these three dietary patterns to incident Alzheimer's disease (AD). METHODS: We investigated the diet-AD relations in a prospective study of 923 participants, ages 58 to 98 years, followed on average 4.5 years. Diet was assessed by a semiquantitative food frequency questionnaire. RESULTS: In adjusted proportional hazards models, the second (hazards ratio or HR = 0.65, 95% confidence interval or CI 0.44, 0.98) and highest tertiles (HR = 0.47, 95% CI 0.26, 0.76) of MIND diet scores had lower rates of AD versus tertile 1, whereas only the third tertiles of the DASH (HR = 0.61, 95% CI 0.38, 0.97) and Mediterranean (HR = 0.46, 95% CI 0.26, 0.79) diets were associated with lower AD rates. DISCUSSION: High adherence to all three diets may reduce AD risk. Moderate adherence to the MIND diet may also decrease AD risk.en-USAgingAlzheimer's diseaseCognitionEpidemiological studyNutritiondietJournal Article2017-02-0710.1016/j.jalz.2014.11.009