Spencer, LisaWeller, Peter2017-08-092010Spencer, Lisa A, and Peter F Weller. 2010. Eosinophils and Th2 Immunity: Contemporary Insights. Immunol Cell Biol 88, no. 3: 250–256. doi:10.1038/icb.2009.115.0818-9641http://nrs.harvard.edu/urn-3:HUL.InstRepos:33730188Eosinophils, innate immune leukocytes elicited by Th2 cells, have long been associated with the effector arm of Th2 immune responses. However, accumulating data over the past decade reveal a much more dynamic picture of Th2 immunity, where eosinophils are present very early in response to Th2-inducing agents and function in the initiation of Th2 immunity. Here we discuss recent data showing immune functions of eosinophils distinct from their previously appreciated tissue- and helminth-destructive capacities, providing strong evidence for a new paradigm of Th2 immunity defined by a dynamic interplay between eosinophils and T cells.en-USJournal Article2017-08-0910.1038/icb.2009.115