Shi, ChenchenLi, HaipengYang, YifuHou, Lifei2015-06-022015Shi, Chenchen, Haipeng Li, Yifu Yang, and Lifei Hou. 2015. “Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives.” Mediators of Inflammation 2015 (1): 435713. doi:10.1155/2015/435713. http://dx.doi.org/10.1155/2015/435713.0962-9351http://nrs.harvard.edu/urn-3:HUL.InstRepos:16121118Artemisinin and its derivatives are widely used in the world as the first-line antimalarial drug. Recently, growing evidences reveal that artemisinin and its derivatives also possess potent anti-inflammatory and immunoregulatory properties. Meanwhile, researchers around the world are still exploring the unknown bioactivities of artemisinin derivatives. In this review, we provide a comprehensive discussion on recent advances of artemisinin derivatives affecting inflammation and autoimmunity, the underlying molecular mechanisms, and also drug development of artemisinins beyond antimalarial functions.en-USJournal Article2015-06-0210.1155/2015/435713