Reddy, Devasis NYonekawa, YoshihiroThomas, Benjamin JNudleman, Eric DWilliams, George A2016-10-112016Reddy, Devasis N, Yoshihiro Yonekawa, Benjamin J Thomas, Eric D Nudleman, and George A Williams. 2016. “Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome.” Clinical Ophthalmology (Auckland, N.Z.) 10 (1): 1531-1534. doi:10.2147/OPTH.S111526. http://dx.doi.org/10.2147/OPTH.S111526.1177-5467http://nrs.harvard.edu/urn-3:HUL.InstRepos:29002581Purpose The aim of the study was to present the long-term anatomical and visual outcomes of retinal detachment repair in patients with Stickler syndrome. Patients and methods This study is a retrospective, interventional, consecutive case series of patients with Stickler syndrome undergoing retinal reattachment surgery from 2009 to 2014 at the Associated Retinal Consultants, William Beaumont Hospital. Results: Sixteen eyes from 13 patients were identified. Patients underwent a mean of 3.1 surgical interventions (range: 1–13) with a mean postoperative follow-up of 94 months (range: 5–313 months). Twelve eyes (75%) developed proliferative vitreoretinopathy. Retinal reattachment was achieved in 100% of eyes, with ten eyes (63%) requiring silicone oil tamponade at final follow-up. Mean preoperative visual acuity (VA) was 20/914, which improved to 20/796 at final follow-up (P=0.81). There was a significant correlation between presenting and final VA (P<0.001), and patients with poorer presenting VA were more likely to require silicone oil tamponade at final follow-up (P=0.04). Conclusion: Repair of retinal detachment in patients with Stickler syndrome often requires multiple surgeries, and visual outcomes are variable. Presenting VA is significantly predictive of long-term VA outcomes.en-USpediatric retinaproliferative vitreoretinopathyretinascleral bucklevitrectomyvitreoretinal surgeryJournal Article2016-10-1110.2147/OPTH.S111526