Narayanaswami, PushpaSpieker, Andrew J.Mongiovi, PhillipKeel, John C.Muzin, StefanRutkove, Seward2017-10-022012Narayanaswami, Pushpa, Andrew J. Spieker, Phillip Mongiovi, John C. Keel, Stefan C. Muzin, and Seward B. Rutkove. 2012. “Utilizing a Handheld Electrode Array for Localized Muscle Impedance Measurements.” Muscle & Nerve 46 (2) (July 16): 257–263. doi:10.1002/mus.23307.0148-639Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:33974340Introduction: Electrical impedance myography (EIM) is a non-invasive technique used for assessment of muscle health in which a high-frequency, low-amplitude electric current is applied to the skin overlying a muscle, and the resulting surface voltage is measured. We have previously used adhesive electrodes, application of which is inconvenient. We present data using a handheld electrode array (HEA) that we devised to expedite the EIM procedure in a clinical setting. Methods: Thirty-four healthy volunteers and 24 radiculopathy subjects underwent EIM testing using the HEA and adhesive electrodes. Results: The HEA was shown to have good test-retest reproducibility, with intraclass correlation coefficients as high as 0.99. HEA data correlated strongly with data from adhesive electrodes, ρ = 0.85 in healthy volunteers (p < 0.001) and ρ = 0.75 in radiculopathy subjects (p < 0.001). Discussion: These data support the potential use of a handheld array for performing rapid localized surface impedance measurements.en-USelectrical impedanceradiculopathysubcutaneous fatmusclereproducibilityJournal Article2017-05-3120122017-10-0210.1002/mus.23307