Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients

Reddy, KrishnaBajwa, EdnanParker, RobertOnderdonk, AndrewWalensky, Rochelle2016-04-012016Reddy, Krishna P., Ednan K. Bajwa, Robert A. Parker, Andrew B. Onderdonk, and Rochelle P. Walensky. 2016. “Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients.” Open Forum Infectious Diseases 3 (1): ofw023. doi:10.1093/ofid/ofw023. http://dx.doi.org/10.1093/ofid/ofw023.2328-8957http://nrs.harvard.edu/urn-3:HUL.InstRepos:26318766Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.en-UScritically illinfluenza diagnosislower respiratory tractupper respiratory tractRelationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza PatientsJournal Article2016-04-0110.1093/ofid/ofw023