Essayed, Walid I.Zhang, FanUnadkat, PrashinCosgrove, G. ReesGolby, AlexandraO'Donnell, Lauren2017-07-242017Essayed, Walid I., Fan Zhang, Prashin Unadkat, G. Rees Cosgrove, Alexandra J. Golby, and Lauren J. O'Donnell. 2017. “White matter tractography for neurosurgical planning: A topography-based review of the current state of the art.” NeuroImage : Clinical 15 (1): 659-672. doi:10.1016/j.nicl.2017.06.011. http://dx.doi.org/10.1016/j.nicl.2017.06.011.http://nrs.harvard.edu/urn-3:HUL.InstRepos:33490860We perform a review of the literature in the field of white matter tractography for neurosurgical planning, focusing on those works where tractography was correlated with clinical information such as patient outcome, clinical functional testing, or electro-cortical stimulation. We organize the review by anatomical location in the brain and by surgical procedure, including both supratentorial and infratentorial pathologies, and excluding spinal cord applications. Where possible, we discuss implications of tractography for clinical care, as well as clinically relevant technical considerations regarding the tractography methods. We find that tractography is a valuable tool in variable situations in modern neurosurgery. Our survey of recent reports demonstrates multiple potentially successful applications of white matter tractography in neurosurgery, with progress towards overcoming clinical challenges of standardization and interpretation.en-USDBS, Deep brain stimulationDES, Direct electrical stimulationDTT, Direct tract targetingFA, Fractional anisotropyFN, Facial nerveWMT, White matter tractographyNeurosurgical planningReviewTractographyWhite matterJournal Article2017-07-2410.1016/j.nicl.2017.06.011