Cannioto, Rikki ALaMonte, Michael JKelemen, Linda ERisch, Harvey AEng, Kevin HMinlikeeva, Albina NHong, Chi-ChenSzender, J BrianSucheston-Campbell, LaraJoseph, Janine MBerchuck, AndrewChang-Claude, JennyCramer, DanielDeFazio, AnnaDiergaarde, BrendaDörk, ThiloDoherty, Jennifer AEdwards, Robert PFridley, Brooke LFriel, GraceGoode, Ellen LGoodman, Marc THillemanns, PeterHogdall, EstridHosono, SatoyoKelley, Joseph LKjaer, Susanne KKlapdor, RüdigerMatsuo, KeitaroOdunsi, KunleNagle, Christina MOlsen, Catherine MPaddock, Lisa EPearce, Celeste LPike, Malcolm CRossing, Mary ASchmalfeldt, BarbaraSegal, Brahm HSzamreta, Elizabeth AThompson, Pamela JTseng, Chiu-ChenVierkant, RobertSchildkraut, Joellen MWentzensen, NicolasWicklund, Kristine GWinham, Stacey JWu, Anna HModugno, FrancesmaryNess, Roberta BJensen, AllanWebb, Penelope MTerry, KathrynBandera, Elisa VMoysich, Kirsten B2017-07-242016Cannioto, R. A., M. J. LaMonte, L. E. Kelemen, H. A. Risch, K. H. Eng, A. N. Minlikeeva, C. Hong, et al. 2016. “Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium.” British Journal of Cancer 115 (1): 95-101. doi:10.1038/bjc.2016.153. http://dx.doi.org/10.1038/bjc.2016.153.http://nrs.harvard.edu/urn-3:HUL.InstRepos:33490967Background: Little is known about modifiable behaviours that may be associated with epithelial ovarian cancer (EOC) survival. We conducted a pooled analysis of 12 studies from the Ovarian Cancer Association Consortium to investigate the association between pre-diagnostic physical inactivity and mortality. Methods: Participants included 6806 women with a primary diagnosis of invasive EOC. In accordance with the Physical Activity Guidelines for Americans, women reporting no regular, weekly recreational physical activity were classified as inactive. We utilised Cox proportional hazard models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) representing the associations of inactivity with mortality censored at 5 years. Results: In multivariate analysis, inactive women had significantly higher mortality risks, with (HR=1.34, 95% CI: 1.18–1.52) and without (HR=1.22, 95% CI: 1.12–1.33) further adjustment for residual disease, respectively. Conclusion: In this large pooled analysis, lack of recreational physical activity was associated with increased mortality among women with invasive EOC.en-USrecreational physical activityinactivityepithelial ovarian cancermortality risksurvivalJournal Article2017-07-2410.1038/bjc.2016.153