Waxmonsky, JeanetteKilbourne, Amy M.Goodrich, David E.Nord, Kristina M.Lai, ZongshanLaird, ChristinaClogston, JuliaKim, Hyungjin MyraMiller, ChristopherBauer, Mark2016-05-312014Waxmonsky, Jeanette, Amy M. Kilbourne, David E. Goodrich, Kristina M. Nord, Zongshan Lai, Christina Laird, Julia Clogston, Hyungjin Myra Kim, Christopher Miller, and Mark S. Bauer. 2014. “Enhanced Fidelity to Treatment for Bipolar Disorder: Results From a Randomized Controlled Implementation Trial.” Psychiatric Services 65 (1) (January): 81–90. doi:10.1176/appi.ps.201300039.1075-2730http://nrs.harvard.edu/urn-3:HUL.InstRepos:27104240Background We determined whether application of a novel implementation intervention (Enhanced Replicating Effective Programs-REP) versus its standard, dissemination-focused version (REP) improved fidelity to bipolar disorder treatment (Life Goals Collaborative Care- LGCC). Methods Five community practices from Michigan and Colorado were randomized to receive LGCC using Enhanced or standard REP. One provider at each practice implemented LGCC which included patient self-management support (4 group sessions focused on symptoms and behavior goals), guideline dissemination to providers, and ongoing phone care management focused on maintaining behavior goals and provider engagement. Standard REP included intervention packaging (i.e., translation of LGCC core components into user-friendly language), training, and as-needed technical assistance. Enhanced REP added customization of LGCC and ongoing, proactive technical assistance through an internal and external facilitator that focused on enhancing provider buy-in and uptake. Multiple and logistic regression analyses determined the impact on patient-level LGCC fidelity between Enhanced versus standard REP. Results Participants (N=384; mean age = 42 years, 67% women, 29% nonwhite) averaged 3.0 out of 4 LGCC group sessions and had 4.0 care management contacts. Enhanced REP implementation was associated with 2.6 (p<.001) greater total number of sessions/contacts than standard REP, which was driven by 2.5 (p<.01) more care management contacts, after adjusting for patient factors. Women and those with a history of homelessness received fewer sessions. Conclusions Enhanced REP implementation was associated with improved LGCC fidelity, primarily for care management contacts. Additional customization of interventions such as LGCC may be needed to ensure adequate treatment fidelity for key vulnerable populations. Go to:en-USJournal Article2016-05-3110.1176/appi.ps.201300039