Reilly, Amanda2015-07-162015-052015-06-262015Reilly, Amanda. 2015. Effective Allocation of Reactive Cholera Vaccines: A One or Two Dose Campaign?. Bachelor's thesis, Harvard College.http://nrs.harvard.edu/urn-3:HUL.InstRepos:17417579Every year for the past five years, over 100,000 cases of cholera have been reported to the World Health Organization (WHO). Though cholera is by no means a new disease, its containment in low-income countries has proved impossible with traditional measures such as WASH interventions. To supplement these far-reaching interventions, the WHO has proposed and begun to amass a reactive vaccine stockpile. As outbreaks are reported, the WHO intends to evaluate them and determine if a reactive vaccination supplement is appropriate. Understanding how to optimally allocate reactive vaccines is essential to the WHO’s evaluation of a country’s need for vaccines. The primary focus of this paper is to determine which conditions are appropriate for one or two dose reactive vaccination campaigns over a variety of parameter values. Though a range of parameter values are examined, the results indicate that the incremental benefit of the second dose is relatively small.application/pdfenMathematicsHealth Sciences, EpidemiologyHealth Sciences, Public HealthThesis or Dissertation2015-11-02