Spieker, Andrew J.Narayanaswami, PushpaFleming, LauraKeel, John C.Muzin, StefanRutkove, Seward2018-07-272013Spieker, Andrew J., Pushpa Narayanaswami, Laura Fleming, John C. Keel, Stefan C. Muzin, and Seward B. Rutkove. 2013. “Electrical Impedance Myography in the Diagnosis of Radiculopathy.” Muscle & Nerve 48 (5) (September 11): 800–805. doi:10.1002/mus.23833.0148-639Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:37309302We sought to determine whether elec- trical impedance myography (EIM) could serve as a diagnostic procedure for evaluation of radiculopathy. Methods: Twenty- seven patients with clinically and radiologically diagnosed cervi- cal or lumbosacral radiculopathy who met a “gold standard” defi- nition underwent EIM and standard needle electromyography (EMG) of multiple upper or lower extremity muscles. Results: EIM reactance values revealed consistent reductions in the radic- ulopathy-affected myotomal muscles as compared with those on the unaffected side; the degree of asymmetry was associated strongly with the degree of EMG abnormality (P<0.001). EIM had a sensitivity of 64.5% and a specificity of 77.0%; in compari- son, EMG had a sensitivity of 79.7% but a specificity of 69.7%. Conclusions: These findings support the potential for EIM to serve as a new non-invasive tool to assist in diagnosis of radicu- lopathy; however, further refinement of the technique is needed for this specific application.en-USJournal Article2018-07-21201310.1002/mus.23833