Campo, GianlucaPavasini, RitaMorciano, GiampaoloLincoff, Michael A.C. Gibson, MichaelKitakaze, MasafumiLonborg, JacobAhluwalia, AmritaIshii, HidekiFrenneaux, MichaelOvize, MichelGalvani, MarcelloAtar, DanIbanez, BorjaCerisano, GiampaoloBiscaglia, SimoneNeil, Brandon J.Asakura, MasanoriEngstrom, ThomasJones, Daniel A.Dawson, DanaFerrari, RobertoPinton, PaoloOttani, Filippo2017-11-212017Campo, G., R. Pavasini, G. Morciano, M. A. Lincoff, M. C. Gibson, M. Kitakaze, J. Lonborg, et al. 2017. “Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention.” Data in Brief 14 (1): 197-205. doi:10.1016/j.dib.2017.07.033. http://dx.doi.org/10.1016/j.dib.2017.07.033.http://nrs.harvard.edu/urn-3:HUL.InstRepos:34375165Mortality and morbidity in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) are still high [1]. A huge amount of the myocardial damage is related to the mitochondrial events happening during reperfusion [2]. Several drugs directly and indirectly targeting mitochondria have been administered at the time of the PCI and their effect on fatal (all-cause mortality, cardiovascular (CV) death) and non fatal (hospital readmission for heart failure (HF)) outcomes have been tested showing conflicting results [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16]. Data from 15 trials have been pooled with the aim to analyze the effect of drug administration versus placebo on outcome [17]. Subgroup analysis are here analyzed: considering only randomized clinical trial (RCT) on cyclosporine or nicorandil [3], [4], [5], [9], [10], [11], excluding a trial on metoprolol [12] and comparing trial with follow-up length <12 months versus those with longer follow-up [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16]. This article describes data related article titled “Clinical Benefit of Drugs Targeting Mitochondrial Function as an Adjunct to Reperfusion in ST-segment Elevation Myocardial Infarction: a Meta-Analysis of Randomized Clinical Trials” [17].en-USReperfusion injuryMyocardial infarctionPCICyclosporinNicorandilFollow-upJournal Article2017-11-2110.1016/j.dib.2017.07.033