Machalaba, CatherineSmith, Kristine MAwada, LinaBerry, KevinBerthe, FranckBouley, Timothy ABruce, MieghanCortiñas Abrahantes, JoseEl Turabi, AnasFeferholtz, YashaFlynn, LouiseFournié, GiullaumeAndre, AmandaGrace, DeliaJonas, OlgaKimani, TabithaLe Gall, FrançoisMiranda, Juan JosePeyre, MarisaPinto, JulioRoss, NoamRüegg, Simon RSalerno, Robert HSeifman, RichardZambrana-Torrelio, CarlosKaresh, William B2018-06-272017Machalaba, C., K. M. Smith, L. Awada, K. Berry, F. Berthe, T. A. Bouley, M. Bruce, et al. 2017. “One Health Economics to confront disease threats.” Transactions of the Royal Society of Tropical Medicine and Hygiene 111 (6): 235-237. doi:10.1093/trstmh/trx039. http://dx.doi.org/10.1093/trstmh/trx039.http://nrs.harvard.edu/urn-3:HUL.InstRepos:37160021Abstract Global economic impacts of epidemics suggest high return on investment in prevention and One Health capacity. However, such investments remain limited, contributing to persistent endemic diseases and vulnerability to emerging ones. An interdisciplinary workshop explored methods for country-level analysis of added value of One Health approaches to disease control. Key recommendations include: 1. systems thinking to identify risks and mitigation options for decision-making under uncertainty; 2. multisectoral economic impact assessment to identify wider relevance and possible resource-sharing, and 3. consistent integration of environmental considerations. Economic analysis offers a congruent measure of value complementing diverse impact metrics among sectors and contexts.en-USEconomicEnvironmentEpidemicMultisectoralOne HealthPreventionJournal Article2018-06-2710.1093/trstmh/trx039