Rosenfeld, LindsayRudd, RimaChew, Ginger L.Emmons, KarenAcevedo-García, Dolores2017-09-222010Rosenfeld, Lindsay, Rima Rudd, Ginger L. Chew, Karen Emmons, and Dolores Acevedo-García. 2010. “Are Neighborhood-Level Characteristics Associated with Indoor Allergens in the Household?” Journal of Asthma 47 (1) (January 25): 66–75. doi:10.3109/02770900903362676.0277-0903http://nrs.harvard.edu/urn-3:HUL.InstRepos:33942648Background Individual home characteristics have been associated with indoor allergen exposure; however, the influence of neighborhood-level characteristics has not been well-studied. We defined neighborhoods as community districts determined by the New York Department of City Planning. Objective We examined the relationship between neighborhood-level characteristics and the presence of dust mite (Der f 1), cat (Fel d 1), cockroach (Bla g 2), and mouse (MUP) allergens in the household. Methods Using data from the Puerto Rican Asthma Project, a birth cohort of Puerto Rican children at risk of allergic sensitization (n=261) we examined associations between neighborhood characteristics (percent tree canopy, asthma hospitalizations per 1000 children, roadway length within 100 meters of buildings, serious housing code violations per 1000 rental units, poverty rates, and felony crime rates) and the presence of indoor allergens. Allergen cutpoints were used for categorical analyses and defined as follows: dust mite: >0.25 μg/g; cat: >1 μg/g; cockroach: >1 U/g; mouse: >1.6 μg/g. Results Serious housing code violations were statistically significantly positively associated with dust mite, cat and mouse allergens (continuous variables), adjusting for mother's income and education, and all neighborhood-level characteristics. In multivariable logistic regression analyses, medium levels of housing code violations were associated with higher dust mite and cat allergens (1.81, 95%CI: 1.08, 3.03 and 3.10, 95%CI: 1.22, 7.92, respectively). A high level of serious housing code violations was associated with higher mouse allergen (2.04, 95%CI: 1.15, 3.62). A medium level of housing code violations was associated with higher cockroach allergen (3.30, 95%CI: 1.11, 9.78). Conclusions Neighborhood-level characteristics, specifically housing code violations, appear to be related to indoor allergens, which may have implications for future research explorations and policy decisions.en-USindoor allergensdust mitecatcockroachmouseasthmaneighborhoodscommunity districtshousing code violationspolicyNew York CityPuerto RicanJournal Article2017-09-0720102017-09-2210.3109/02770900903362676