Kubaisi, BuraaMaleki, ArashAhmed, AseefLamba, NeelSahawneh, HaithamStephenson, AndrewMontieth, AlyssaTopgi, ShobhaFoster, Charles2018-06-272018Kubaisi, Buraa, Arash Maleki, Aseef Ahmed, Neel Lamba, Haitham Sahawneh, Andrew Stephenson, Alyssa Montieth, Shobha Topgi, and C Stephen Foster. 2018. “Ahmed glaucoma valve in uveitic patients with fluocinolone acetonide implant-induced glaucoma: 3-year follow-up.” Clinical Ophthalmology (Auckland, N.Z.) 12 (1): 799-804. doi:10.2147/OPTH.S152035. http://dx.doi.org/10.2147/OPTH.S152035.http://nrs.harvard.edu/urn-3:HUL.InstRepos:37160292Purpose To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) in eyes with noninfectious uveitis that had fluocinolone acetonide intravitreal implant (Retisert™)-induced glaucoma. Methods: This retrospective study reviewed the safety and efficacy of AGV implantation in patients with persistently elevated intraocular pressure (IOP) after implantation of a fluocinolone acetonide intravitreal implant at the Massachusetts Eye Research and Surgery Institution between August 2006 and November 2015. Results: Nine patients with 10 uveitic eyes were included in this study, none of which had preexisting glaucoma in the study eye. Mean patient age was 42 years; 6 patients were female and 3 were male. Baseline mean IOP was 30.6 mmHg prior to AGV placement while mean IOP-lowering medications were 2.9. In the treatment groups, there was a statistically significant reduction in post-AGV IOP. IOP was lowest at 1-week after AGV implantation (9.0 mmHg). Nine out of 10 eyes achieved an IOP below target value of 22 mmHg and/or a 20% reduction in IOP from baseline 1 month and 1 year following AGV placement. All other postoperative time points showed all 10 eyes reaching this goal. A statistically significant decrease in IOP-lowering medication was seen at the 1-week, 1-month, and 3-year time points compared to baseline, while a statistically significant increase was seen at the 3-month, 6-month, and 2-year post-AGV time points. No significant change in retinal nerve thickness or visual field analysis was found. Conclusion: AGV is an effective and safe method of treatment in fluocinolone acetonide intravitreal implant-induced glaucoma. High survival rate is expected for at least 3 years.en-USuveitisglaucomaAhmed glaucoma valvefluocinolone acetonide intravitreal implantocular inflammationJournal Article2018-06-2710.2147/OPTH.S152035