Abuabara, K.Yu, A. M.Okhovat, J.‐P.Allen, I. E.Langan, S. M.2018-04-192017Abuabara, K., A. M. Yu, J.‐P. Okhovat, I. E. Allen, and S. M. Langan. 2017. “The prevalence of atopic dermatitis beyond childhood: A systematic review and meta‐analysis of longitudinal studies.” Allergy 73 (3): 696-704. doi:10.1111/all.13320. http://dx.doi.org/10.1111/all.13320.http://nrs.harvard.edu/urn-3:HUL.InstRepos:35982065Abstract Background: There are sparse and conflicting data regarding the long‐term clinical course of atopic dermatitis (AD). Although often described as a childhood disease, newer population‐based estimates suggest the prevalence of pediatric and adult disease may be similar. Methods: Our objective was to determine whether there is a decline in the prevalence of AD in population‐based cohorts of patients followed longitudinally beyond childhood. We conducted a systematic review and meta‐analysis including studies assessing AD prevalence across 3 or more points in time. The primary outcome was weighted overall risk difference (percentage decrease in AD prevalence). Results: Of 2080 references reviewed, 7 studies with 13 515 participants were included. Participants were assessed at 3‐6 time points, ranging from age 3 months to 26 years. The percentage decrease in prevalence after age 12 was 1%, which was not significantly different from zero (95% confidence interval −2%‐5%). Similar results were found with other age cut‐offs. Conclusion: The prevalence of AD in longitudinal birth cohort studies is similar in childhood and adolescence/early adulthood.en-USOriginal Articleatopic dermatitisatopic eczemaeczemanatural historyprevalenceJournal Article2018-04-1910.1111/all.13320