Piantadosi, AnneKanjilal, SanjatGanesh, VijayKhanna, ArjunHyle, EmilyRosand, JonathanBold, TylerMetsky, Hayden CLemieux, JacobLeone, Michael JFreimark, LisaMatranga, Christian BAdams, GordonMcGrath, GrahamZamirpour, SiavashTelford, SamRosenberg, EricCho, Tracey AlexanderFrosch, MatthewGoldberg, MarciaMukerji, ShibaniSabeti, Pardis2018-04-192017Piantadosi, A., S. Kanjilal, V. Ganesh, A. Khanna, E. P. Hyle, J. Rosand, T. Bold, et al. 2017. “Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing.” Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 66 (5): 789-792. doi:10.1093/cid/cix792. http://dx.doi.org/10.1093/cid/cix792.http://nrs.harvard.edu/urn-3:HUL.InstRepos:35982225Abstract We describe a patient with severe and progressive encephalitis of unknown etiology. We performed rapid metagenomic sequencing from cerebrospinal fluid and identified Powassan virus, an emerging tick-borne flavivirus that has been increasingly detected in the United States.en-USPowassan virusencephalitismetagenomic sequencingJournal Article2018-04-1910.1093/cid/cix792