Colleran, Gabrielle C.Kwatra, NehaOberg, LeahGrant, FrederickDrubach, LauraCallahan, MichaelMacDougall, Robert D.Fahey, FredericVoss, Stephan2017-12-062017Colleran, Gabrielle C., Neha Kwatra, Leah Oberg, Frederick D. Grant, Laura Drubach, Michael J. Callahan, Robert D. MacDougall, Frederic H. Fahey, and Stephan D. Voss. 2017. “How we read pediatric PET/CT: indications and strategies for image acquisition, interpretation and reporting.” Cancer Imaging 17 (1): 28. doi:10.1186/s40644-017-0130-8. http://dx.doi.org/10.1186/s40644-017-0130-8.http://nrs.harvard.edu/urn-3:HUL.InstRepos:34492955PET/CT plays an important role in the diagnosis, staging and management of many pediatric malignancies. The techniques for performing PET/CT examinations in children have evolved, with increasing attention focused on reducing patient exposure to ionizing radiation dose whenever possible and minimizing scan duration and sedation times, with a goal toward optimizing the overall patient experience. This review outlines our approach to performing PET/CT, including a discussion of the indications for a PET/CT exam, approaches for optimizing the exam protocol, and a review of different approaches for acquiring the CT portion of the PET/CT exam. Strategies for PACS integration, image display, interpretation and reporting are also provided. Most practices will develop a strategy for performing PET/CT that best meets their respective needs. The purpose of this article is to provide a comprehensive overview for radiologists who are new to pediatric PET/CT, and also to provide experienced PET/CT practitioners with an update on state-of-the art CT techniques that we have incorporated into our protocols and that have enabled us to make considerable improvements to our PET/CT practice.en-USPET/CTDiagnostic CTPediatric oncologyHybrid imagingDose reductionAttenuation correctionMultidisciplinary interpretationJournal Article2017-12-0610.1186/s40644-017-0130-8