Chen, Shih-HengPearson, AngelaCoen, Donald M.Chen, Shun-Hua2019-10-052004Chen, S.-H., A. Pearson, D. M. Coen, and S.-H. Chen. 2003. “Failure of Thymidine Kinase-Negative Herpes Simplex Virus To Reactivate from Latency Following Efficient Establishment.” Journal of Virology 78 (1): 520–23. https://doi.org/10.1128/jvi.78.1.520-523.2004.0022-538X1070-63211098-5514http://nrs.harvard.edu/urn-3:HUL.InstRepos:41482989Thymidine kinase-negative mutants of herpes simplex virus did not reactivate from latency in mouse trigeminal ganglia, even when their latent viral loads were comparable to those that permitted reactivation by wild-type virus. Thus, reduced establishment of latency does not suffice to account for the failure to reactivate.en-USJournal Article2019-10-0510.1128/JVI.78.1.520-523.2004