Michor, FranziskaTemko, DanielMoorhead, Graydon2022-07-2020222022-06-032022Moorhead, Graydon. 2022. Exploring Radiation’s Effects on Lung Cancer, with a focus on Motility and Migration. Bachelor's thesis, Harvard College.29062962https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372704Lung cancer is one of the deadliest forms of cancer. A common therapeutic agent is radiation, but there is beginning to be more and more evidence about how radiation can actually have effects on motility and migration, increasing the risk for metastasis. To explore this, a model of lung cancer was built using A549 cells. It was found that high dose, intensive hypofractionated radiation schedules can lead to more cell death, but have the effect of leaving the tumor in a highly dispersed state as compared to lower intensity, hyperfractionated radiations schedules.application/pdfenA549Lung CancerMigrationMotilityRadiationBiologyThesis or Dissertation2022-07-20