An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function

Kambali, MalteshLi, YanUnichenko, PetrFeria Pliego, Jessica A.Yadav, RachitaLiu, JingMcGuinness, PatrickCobb, Johanna G.Wang, MuxiaoNagarajan, RajasekarLyu, JinruiVongsouthi, VanessaJackson, Colin J.Engin, ElifCoyle, Joseph T.Shin, JaeweonHodgson, NathanielHensch, TakaoTalkowski, Michael E.Homanics, Gregg E.Bolshakov, Vadim Y.Henneberger, ChristianRudolph, Uwe2025-02-072024-08-30Kambali, Maltesh, Yan Li, Petr Unichenko, Jessica A. Feria Pliego, Rachita Yadav, Jing Liu, Patrick McGuinness et al. "An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function." Mol Psychiatry No Volume. DOI: 10.1038/s41380-024-02711-51359-41841476-5578https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37380320Keeps timing out so here is the complete list of Authors: Maltesh Kambali, Yan Li, Petr Unichenko, Jessica Feria Pliego, Rachita Yadav, Jing Liu, Patrick McGuinness, Johanna Cobb, Muxiao Wang, Rajasekar Nagarajan, Jinrui Lyu, Vanessa Vongsouthi, Colin Jackson, Elif Engin, Joseph T. Coyle, Jaeweon Shin, Nathaniel Hodgson, Takao Hensch, Michael Talkowski, Gregg Homanics, Vadim Bolshakov, Christian Henneberger and Uwe Rudolph Manuscript Number: 2023MP002124Ren-USAn increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor functionJournal Article2025-02-0710.1038/s41380-024-02711-5