Now showing items 1-19 of 19

    • Analysis of Multiple-cycle Data From Couples Undergoing In Vitro Fertilization 

      Missmer, Stacey Ann; Pearson, Kimberly Hope; Ryan, Louise Marie; Meeker, John D.; Cramer, Daniel William; Hauser, Russ B. (Ovid Technologies (Wolters Kluwer Health), 2011)
      The number of in vitro fertilization (IVF) cycles in the U.S. increased from fewer than 46,000 in 1995 to more than 120,000 in 2005. IVF and other assisted reproductive technology (ART) data are routinely collected and ...
    • Cumulative Exposure to Lead in Relation to Cognitive Function in Older Women 

      Weuve, Jennifer Lynn; Korrick, Susan Abigail; Weisskopf, Marc G.; Ryan, Louise Marie; Schwartz, Joel David; Nie, Huiling; Grodstein, Francine; Hu, Howard (National Institute of Environmental Health Sciences, 2008)
      Background: Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women. Objective: We examined biomarkers of lead ...
    • Diversity of the Gut Microbiota and Eczema in Early Life 

      Forno, Erick; Onderdonk, Andrew Bruce; McCracken, John Patrick; Litonjua, Augusto Ampil; Laskey, Daniel; Delaney, Mary Louise Rodriguez; DuBois, Andrea M; Gold, Diane R.; Ryan, Louise Marie; Weiss, Scott Tillman; Celedón, Juan C (BioMed Central, 2008)
      Background: A modest number of prospective studies of the composition of the intestinal microbiota and eczema in early life have yielded conflicting results. Objective: To examine the relationship between the bacterial ...
    • Do Recent Data from the Seychelles Islands Alter the Conclusions of the NRC Report on the Toxicological Effects of Methylmercury? 

      Stern, Alan H.; Jacobson, Joseph L.; Ryan, Louise Marie; Burke, Thomas A. (BioMed Central, 2004)
      In 2000, the National Research Council (NRC), an arm of the National Academy of Sciences, released a report entitled, "Toxicological Effects of Methylmercury." The overall conclusion of that report was that, at levels of ...
    • Does Living Near a Superfund Site Contribute to Higher Polychlorinated Biphenyl (PCB) Exposure? 

      Tolbert, Paige E.; Choi, Anna L; Choi, Anna Lai; Levy, Jonathan Ian; Dockery, Douglas W.; Ryan, Louise Marie; Altshul, Larisa; Korrick, Susan Abigail (National Institute of Environmental Health Sciences, 2006)
      We assessed determinants of cord serum polychlorinated biphenyl (PCB) levels among 720 infants born between 1993 and 1998 to mothers living near a PCB-contaminated Superfund site in Massachusetts, measuring the sum of 51 ...
    • Dose–Response Relationship of Prenatal Mercury Exposure and IQ: An Integrative Analysis of Epidemiologic Data 

      Axelrad, Daniel A.; Bellinger, David C.; Ryan, Louise Marie; Woodruff, Tracey J. (National Institute of Environmental Health Sciences, 2007)
      Background: Prenatal exposure to mercury has been associated with adverse childhood neurologic outcomes in epidemiologic studies. Dose–response information for this relationship is useful for estimating benefits of reduced ...
    • The Effect of Dose and Timing of Dose on the Association between Airborne Particles and Survival 

      Schwartz, Joel David; Coull, Brent Andrew; Laden, Francine; Ryan, Louise Marie (2008)
      BACKGROUND: Understanding the shape of the concentration–response curve for particles is important for public health, and lack of such understanding was recently cited by U.S. Environmental Protection Agency (EPA) as a ...
    • Effect of Environmental Tobacco Smoke on Levels of Urinary Hormone Markers 

      Wang, Xiaobin; Wang, Lihua; Yang, Fan; Tang, Genfu; Xing, Houxun; Lasley, Bill; Overstreet, James W.; Stanford, Joseph B.; Chen, ChangFeng; Ryan, Louise Marie; Xu, Xiang (National Institute of Environmental Health Sciences, 2005)
      Our recent study showed a dose–response relationship between environmental tobacco smoke (ETS) and the risk of early pregnancy loss. Smoking is known to affect female reproductive hormones. We explored whether ETS affects ...
    • Environmental Organochlorines and Semen Quality: Results of a Pilot Study 

      Hauser, Russ B.; Altshul, Larisa M.; Chen, Zuying; Ryan, Louise Marie; Overstreet, James; Schiff, Isaac; Christiani, David C. (National Institute of Environmental Health Sciences, 2002)
      There have been numerous studies that suggest that sperm concentrations (sperm counts) are declining in men. However, other studies suggest that sperm counts are not declining or may be increasing in some areas. Although ...
    • Evaluating the effect of neighbourhood weight matrices on smoothing properties of Conditional Autoregressive (CAR) models 

      Earnest, Arul; Morgan, Geoff; Mengersen, Kerrie; Ryan, Louise Marie; Summerhayes, Richard; Beard, John (BioMed Central, 2007)
      Background: The Conditional Autoregressive (CAR) model is widely used in many small-area ecological studies to analyse outcomes measured at an areal level. There has been little evaluation of the influence of different ...
    • Fungal Levels in the Home and Allergic Rhinitis by 5 Years of Age 

      Stark, Paul C.; Celedón, Juan C.; Chew, Ginger L.; Ryan, Louise Marie; Burge, Harriet A.; Muilenberg, Michael L.; Gold, Diane R. (National Institute of Environmental Health Sciences, 2005)
      Studies have repeatedly demonstrated that sensitization to fungi, such as Alternaria, is strongly associated with allergic rhinitis and asthma in children. However, the role of exposure to fungi in the development of ...
    • The Impact of Diet and Betel Nut Use on Skin Lesions Associated with Drinking-Water Arsenic in Pabna, Bangladesh 

      McCarty, Kathleen M.; Houseman, Eugene Andres; Quamruzzaman, Quazi; Rahman, Mahmuder; Mahiuddin, Golam; Smith, Thomas J.; Ryan, Louise Marie; Christiani, David C. (National Institute of Environmental Health Sciences, 2005)
      An established exposure–response relationship exists between water arsenic levels and skin lesions. Results of previous studies with limited historical exposure data, and laboratory animal studies suggest that diet may ...
    • Mode of Delivery and Cord Blood Cytokines: A Birth Cohort Study 

      Ly, Ngoc P; Ruiz-Pérez, Begoña; Tzianabos, Arthur O; Liang, Catherine; Laskey, Daniel; DuBois, Andrea M; Levy, Hara; Celedón, Juan C; Onderdonk, Andrew Bruce; Litonjua, Augusto Ampil; Delaney, Mary Louise Rodriguez; Gold, Diane R.; Ryan, Louise Marie; Weiss, Scott Tillman (BioMed Central, 2006)
      Background: The mechanisms for the association between birth by cesarean section and atopy and asthma are largely unknown. Objective: To examine whether cesarean section results in neonatal secretion of cytokines that are ...
    • Perceived Neighborhood Safety and Incident Mobility Disability Among Elders: The Hazards of Poverty 

      Clark, Cheryl; Kawachi, Ichiro; Ryan, Louise Marie; Ertel, Karen Ann; Fay, Martha Elizabeth; Berkman, Lisa Faye (BioMed Central, 2009)
      Background: We investigated whether lack of perceived neighborhood safety due to crime, or living in high crime neighborhoods was associated with incident mobility disability in elderly populations. We hypothesized that ...
    • The relationship between environmental exposures to phthalates and DNA damage in human sperm using the neutral comet assay. 

      Duty, Susan M.; Singh, Narendra P; Silva, Manori J; Barr, Dana B; Brock, John W; Ryan, Louise Marie; Herrick, Robert F.; Christiani, David C.; Hauser, Russ B. (2003)
      Phthalates are industrial chemicals widely used in many commercial applications. The general population is exposed to phthalates through consumer products as well as through diet and medical treatments. To determine whether ...
    • The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and \(p,p'\)-DDE 

      Hauser, Russ B.; Chen, Zuying; Pothier, Lucille J.; Ryan, Louise Marie; Altshul, Larisa M. (2003)
      Scientific and public concern exists about potential reproductive health effects of persistent chlorinated organic chemicals, such as polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT), and ...
    • The Relationship of Urinary Metabolites of Carbaryl/Naphthalene and Chlorpyrifos with Human Semen Quality 

      Meeker, John D.; Ryan, Louise Marie; Barr, Dana B.; Herrick, Robert F.; Bennett, Deborah H.; Bravo, Roberto; Hauser, Russ B. (The National Institute of Environmental Health Sciences, 2004)
      Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure ...
    • Serum and Follicular Fluid Organochlorine Concentrations Among Women Undergoing Assisted Reproduction Technologies 

      Meeker, John D; Missmer, Stacey Ann; Altshul, Larisa M.; Vitonis, Allison F; Ryan, Louise Marie; Cramer, Daniel William; Hauser, Russ B. (BioMed Central, 2009)
      Background: Exposure to persistent organic pollutants, including polychlorinated biphenyls (PCBs) and organochlorine pesticides, is widespread among the general population. There is evidence of adverse effects on reproduction ...
    • Within-home versus between-home variability of house dust endotoxin in a birth cohort 

      Abraham, Joseph H.; Gold, Diane R.; Dockery, Douglas W.; Ryan, Louise Marie; Park, Ju-Hyeong; Milton, Donald Kirby (National Institute of Environmental Health Sciences, 2005)
      Endotoxin exposure has been proposed as an environmental determinant of allergen responses in children. To better understand the implications of using a single measurement of house dust endotoxin to characterize exposure ...