Browsing by Author "Diao, Nancy"
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Association Test Based on SNP Set: Logistic Kernel Machine Based Test vs. Principal Component Analysis
Zhao, Yang; Chen, Feng; Zhai, Rihong; Lin, Xihong; Diao, Nancy; Christiani, David C. (Public Library of Science, 2012)GWAS has facilitated greatly the discovery of risk SNPs associated with complex diseases. Traditional methods analyze SNP individually and are limited by low power and reproducibility since correction for multiple comparisons ... -
Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach
Zhao, Yang; Yu, Hao; Zhu, Ying; Ter-Minassian, Monica; Peng, Zhihang; Shen, Hongbing; Diao, Nancy; Chen, Feng (Public Library of Science, 2012)Family based association study (FBAS) has the advantages of controlling for population stratification and testing for linkage and association simultaneously. We propose a retrospective multilevel model (rMLM) approach to ... -
Prenatal Metals Exposure and Child Birth and Growth in Bangladesh
Diao, Nancy (2015-04-24)The objective of this dissertation is to contribute to ongoing research on prenatal metals exposure, in terms of arsenic, lead, and manganese, and infant health and growth, and to deepen the understanding of the complexity ... -
A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh
Kile, Molly L; Rodrigues, Ema G; Mazumdar, Maitreyi; Dobson, Christine B; Diao, Nancy; Golam, Mostofa; Quamruzzaman, Quazi; Rahman, Mahmudar; Christiani, David C (BioMed Central, 2014)Background: Arsenic, a common groundwater pollutant, is associated with adverse reproductive health but few studies have examined its effect on maternal health. Methods: A prospective cohort was recruited in Bangladesh ...