Now showing items 1-3 of 3

    • Barcoding cells using cell-surface programmable DNA-binding domains 

      Mali, Prashant; Aach, John; Lee, Jehyuk; Levner, Daniel; Nip, Lisa; Church, George M. (2013)
      We develop here a novel approach to barcode large numbers of cells through cell-surface expression of programmable zinc-finger DNA-binding domains (sZFs). We show sZFs enable double-stranded DNA to sequence-specifically ...
    • How Accurate Can Genetic Predictions Be? 

      Dreyfuss, Jonathan M; Levner, Daniel; Galagan, James E; Church, George McDonald; Ramoni, Marco F (BioMed Central, 2012)
      Background: Pre-symptomatic prediction of disease and drug response based on genetic testing is a critical component of personalized medicine. Previous work has demonstrated that the predictive capacity of genetic testing ...
    • Universal computing by DNA origami robots in a living animal 

      Amir, Yaniv; Ben-Ishay, Eldad; Levner, Daniel; Ittah, Shmulik; Abu-Horowitz, Almogit; Bachelet, Ido (2014)
      Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines ...