Now showing items 1-6 of 6

    • Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination 

      Mahan, Alison E.; Jennewein, Madeleine F.; Suscovich, Todd; Dionne, Kendall; Tedesco, Jacquelynne; Chung, Amy W.; Streeck, Hendrik; Pau, Maria; Schuitemaker, Hanneke; Francis, Don; Fast, Patricia; Laufer, Dagna; Walker, Bruce D.; Baden, Lindsey; Barouch, Dan H.; Alter, Galit (Public Library of Science, 2016)
      Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the ...
    • Green Herring Syndrome: Bacterial Infection in Patients With Mucormycosis Cavitary Lung Disease 

      Peixoto, Driele; Hammond, Sarah P.; Issa, Nicolas C.; Madan, Rachna; Gill, Ritu R.; Milner, Danny A.; Colson, Yolonda L.; Koo, Sophia; Baden, Lindsey R.; Marty, Francisco M. (Oxford University Press, 2014)
      Mucormycosis is a life-threatening fungal disease in patients with hematological malignancies. The diagnosis of pulmonary mucormycosis is particularly challenging. We describe 3 mucormycosis cases with an uncommon presentation ...
    • Molecular Methods To Improve Diagnosis and Identification of Mucormycosis 

      Hammond, Sarah Page; Bialek, Ralf; Milner, Danny Arnold; Petschnigg, Eva M.; Baden, Lindsey Robert; Marty, Francisco Miguel (American Society for Microbiology, 2011)
      Mucormycosis is difficult to diagnose. Samples from suspected cases often fail to grow Mucorales in microbiologic cultures. We identified all hematologic malignancy and stem cell transplant patients diagnosed with proven ...
    • Risks Associated With Lentiviral Vector Exposures and Prevention Strategies 

      Schlimgen, Ryan; Howard, John; Wooley, Dawn; Thompson, Maureen; Baden, Lindsey R.; Yang, Otto O.; Christiani, David C.; Mostoslavsky, Gustavo; Diamond, David V.; Duane, Elizabeth Gilman; Byers, Karen; Winters, Thomas; Gelfand, Jeffrey A.; Fujimoto, Gary; Hudson, T. Warner; Vyas, Jatin M. (Lippincott Williams & Wilkins, 2016)
      Lentiviral vectors (LVVs) are powerful genetic tools that are being used with greater frequency in biomedical laboratories and clinical trials. Adverse events reported from initial clinical studies provide a basis for risk ...
    • Sequence-Based Discovery of Bradyrhizobium enterica in Cord Colitis Syndrome 

      Bhatt, Ami Bharat; Freeman, Sam Spenser Sharpe; Herrera, Alex Francisco; Pedamallu, Chandra Sekhar; Gevers, Dirk; Duke, Fujiko; Jung, Joonil; Michaud, Monia; Walker, Bruce David; Young, Sally U.; Earl, Ashlee M.; Kostic, Aleksander D.; Ojesina, Akinyemi Ifedapo; Hasserjian, Robert Paul; Ballen, Karen Kuhn; Chen, Yi-Bin Albert; Hobbs, Gabriela; Antin, Joseph Harry; Soiffer, Robert Jon; Baden, Lindsey Robert; Garrett, Wendy S.; Hornick, Jason L.; Marty, Francisco Miguel; Meyerson, Matthew Langer (New England Journal of Medicine (NEJM/MMS), 2013)
      BACKGROUND—Immunosuppression is associated with a variety of idiopathic clinical syndromes that may have infectious causes. It has been hypothesized that the cord colitis syndrome, a complication of umbilical-cord ...
    • Structural Basis for Continued Antibody Evasion by the SARS-CoV-2 Receptor-Binding Domain 

      Nabel, Katherine G.; Clark, Sarah A.; Shankar, Sundaresh; Pan, Junhua; Clark, Lars; Yang, Pan; Coscia, Adrian; McKay, Lindsay G.A.; Varnum, Haley; Brusic, Vesna; Tolan, Nicole V.; Zhou, Guohai; Desjardins, Michaël; Turbett, Sarah E.; Kanjilal, Sanjat; Sherman, Amy; Dighe, Anand; LaRocque, Regina C.; Ryan, Edward; Tylek, Casey; Cohen-Solal, Joel F.; Darcy, Andhao T.; Tavella, Davide; Clabbers, Anca; Fan, Yao; Griffiths, Anthony; Correia, Ivan R.; Seagal, Jane; Baden, Lindsey; Charles, Richelle; Abraham, Jonathan (2021-12-02)
      Many studies have examined the impact of SARS-CoV-2 variants on neutralizing antibody activity after they have become dominant strains. Here, we evaluate the consequences of further viral evolution. We demonstrate mechanisms ...