Browsing by Author "DiCarlo, James"
Now showing items 1-4 of 4
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Emergence of Reward Coding in the Olfactory System
Millman, Daniel Joseph (2016-05-17)Identifying dangerous or rewarding elements in an animal’s surroundings is an important – if not primary – function of sensory systems. This holds particularly true for the mouse olfactory system since odors convey crucial ... -
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
DiCarlo, James; Norville, Julie; Mali, Prashant; Rios Villanueva, Xavier; Aach, John Dennis; Church, George McDonald (Oxford University Press, 2013)Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) systems in bacteria and archaea use RNA-guided nuclease activity to provide adaptive immunity against invading foreign nucleic ... -
Object Selectivity of Local Field Potentials and Spikes in the Macaque Inferior Temporal Cortex
Kreiman, Gabriel; Hung, Chou P.; Kraskov, Alexander; Quiroga, Rodrigo Quian; Poggio, Tomaso; DiCarlo, James (Elsevier BV, 2006)Local field potentials (LFPs) arise largely from dendritic activity over large brain regions and thus provide a measure of the input to and local processing within an area. We characterized LFPs and their relationship to ... -
Safeguarding CRISPR-Cas9 gene drives in yeast
DiCarlo, James E.; Chavez, Alejandro; Dietz, Sven L.; Esvelt, Kevin M.; Church, George M. (2015)RNA-guided gene drives capable of spreading genomic alterations made in laboratory organisms through wild populations in an inheritable way could be used to control populations of organisms that cause environmental and ...