Browsing by Author "Watnick, Paula"
Now showing items 1-3 of 3
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A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity
Ymele-Leki, Patrick; Cao, Shugeng; Sharp, Jared D'Alonzo; Lambert, Kathleen G; McAdam, Alexander John; Husson, Robert N; Tamayo, Giselle; Clardy, Jon C.; Watnick, Paula Ivonne (Public Library of Science, 2012)Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and ... -
Mutations in the IMD Pathway and Mustard Counter Vibrio cholerae Suppression of Intestinal Stem Cell Division in Drosophila
Wang, Zhipeng; Hang, Saiyu; Purdy, Alexandra E.; Watnick, Paula I. (American Society of Microbiology, 2013)ABSTRACT Vibrio cholerae is an estuarine bacterium and an intestinal pathogen of humans that causes severe epidemic diarrhea. In the absence of adequate mammalian models in which to study the interaction of V. cholerae ... -
A sigma factor and anti-sigma factor that control swarming motility and biofilm formation in Pseudomonas aeruginosa
McGuffie, Bryan A. (2015-05-20)Pseudomonas aeruginosa is an environmental bacterium and opportunistic human pathogen of major clinical significance. It is the principal cause of morbidity and mortality in patients with cystic fibrosis (CF) and a leading ...