Browsing by Author "Ran, Chongzhao"
Now showing items 1-5 of 5
-
Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
Zhang, Xueli; Kuo, Chaincy; Moore, Anna; Ran, Chongzhao (MyJove Corporation, 2014)Brown adipose tissue (BAT), widely known as a “good fat” plays pivotal roles for thermogenesis in mammals. This special tissue is closely related to metabolism and energy expenditure, and its dysfunction is one important ... -
Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning
Zhang, Xueli; Tian, Yanli; Zhang, Hongbin; Kavishwar, Amol; Lynes, Matthew; Brownell, Anna-Liisa; Sun, Hongbin; Tseng, Yu-Hua; Moore, Anna; Ran, Chongzhao (Nature Publishing Group, 2015)Manipulation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) can be promising new approaches to counter metabolic disorder diseases in humans. Imaging probes that could consistently monitor BAT ... -
Imaging hydrogen peroxide in Alzheimer’s disease via cascade signal amplification
Yang, Jian; Yang, Jing; Liang, Steven H.; Xu, Yungen; Moore, Anna; Ran, Chongzhao (Nature Publishing Group, 2016)In brains of Alzheimer’s disease (AD), reactive oxygen species (ROS) levels are significantly higher than that of healthy brains. Evidence suggests that, during AD onset and progression, a vicious cycle revolves around ... -
In Vivo Optical Imaging of Interscapular Brown Adipose Tissue with 18F-FDG via Cerenkov Luminescence Imaging
Zhang, Xueli; Kuo, Chaincy; Moore, Anna V.; Ran, Chongzhao (Public Library of Science, 2013)Objective: Brown adipose tissue (BAT), a specialized tissue for thermogenesis, plays important roles for metabolism and energy expenditure. Recent studies validated BAT’s presence in human adults, making it an important ... -
In Vivo Photoactivation Without “Light”: Use of Cherenkov Radiation to Overcome the Penetration Limit of Light
Ran, Chongzhao; Zhang, Zhaoda; Hooker, Jacob M; Moore, Anna V. (Springer Nature, 2011)Purpose: The poor tissue penetration of visible light has been a major barrier for optical imaging, photoactivatable conversions, and photodynamic therapy for in vivo targets with depths beyond 10 mm. In this report, as a ...