Browsing by Author "Churchill, Susanne"

Now showing items 1-5 of 5

    • Development of phenotype algorithms using electronic medical records and incorporating natural language processing 

      Liao, Katherine P; Cai, Tianxi; Savova, Guergana K; Murphy, Shawn N; Karlson, Elizabeth W; Ananthakrishnan, Ashwin N; Gainer, Vivian S; Shaw, Stanley Y; Xia, Zongqi; Szolovits, Peter; Churchill, Susanne; Kohane, Isaac (BMJ Publishing Group Ltd., 2015)
      Electronic medical records are emerging as a major source of data for clinical and translational research studies, although phenotypes of interest need to be accurately defined first. This article provides an overview of ...

    • Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: A pilot study 

      Hoogenboom, Wouter S.; Perlis, Roy; Smoller, Jordan W; Zeng-Treitler, Qing; Gainer, Vivian S.; Murphy, Shawn Norman; Churchill, Susanne E.; Kohane, Isaac Samuel; Shenton, Martha Elizabeth; Iosifescu, Dan (Elsevier BV, 2013)
      For certain research questions related to long-term outcomes or to rare disorders, designing prospective studies is impractical or prohibitively expensive. Such studies could instead utilize clinical and magnetic resonance ...

    • High-Throughput Phenotyping With Electronic Medical Record Data Using a Common Semi-Supervised Approach (PheCAP) 

      Zhang, Yichi; Cai, Tianrun; Yu, Sheng; Cho, Kelly; Hong, Chuan; Sun, Jiehuan; Huang, Jie; Xia, Zongqi; Castro, Victor; Gagnon, David; Savova, Guergana; Churchill, Susanne; Gaziano, John; Kohane, Isaac; Cai, Tianxi; Ho, Yuk-Lam; Ananthakrishnan, Ashwin; Shaw, Stanley; Gainer, Vivian; Link, Nicholas; Honerlaw, Jacqueline; Huong, Sicong; Karlson, Elizabeth; Plenge, Robert; Szolovits, Peter; O'Donnell, Christopher; Murphy, Shawn; Liao, Katherine (Springer Science and Business Media LLC, 2019-11-20)
      Phenotypes are the foundation for clinical and genetic studies of disease risk and outcomes. The growth of biobanks linked to electronic medical record (EMR) data has both facilitated and increased the demand for efficient, ...

    • Improving Case Definition of Crohnʼs Disease and Ulcerative Colitis in Electronic Medical Records Using Natural Language Processing 

      Ananthakrishnan, Ashwin; Cai, Tianxi; Savova, Guergana; Cheng, Su-Chun; Chen, Pei; Guzman, Raul; Gainer, Vivian S.; Murphy, Shawn; Szolovits, Peter; Xia, Zongqi; Shaw, Stanley; Churchill, Susanne; Karlson, Elizabeth; Kohane, Isaac; Plenge, Robert M.; Liao, Katherine (Oxford University Press (OUP), 2013-06)
      Introduction Prior studies identifying patients with inflammatory bowel disease (IBD) utilizing administrative codes have yielded inconsistent results. Our objective was to develop a robust electronic medical record (EMR) ...

    • Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohn’s Disease 

      Ananthakrishnan, Ashwin; Cagan, Andrew; Gainer, Vivian S.; Cai, Tianxi; Cheng, Su-Chun; Savova, Guergana; Chen, Pei; Szolovits, Peter; Xia, Zongqi; De Jager, Philip; Shaw, Stanley; Churchill, Susanne; Karlson, Elizabeth; Kohane, Isaac; Plenge, Robert; Murphy, Shawn; Liao, Katherine (Oxford University Press (OUP), 2013-08-01)
      Introduction Vitamin D may have an immunological role in Crohn’s disease (CD) and ulcerative colitis (UC). Retrospective studies suggested a weak association between vitamin D status and disease activity but have significant ...