Browsing by Author "Mordes, Daniel"

Now showing items 1-4 of 4

    • ALS-Implicated Protein TDP-43 Sustains Levels of STMN2, a Mediator of Motor Neuron Growth and Repair 

      Limone, Francesco; Guerra San Juan, Irune; Burberry, Aaron; Kirchner, Rory; Chen, Kuchuan; Eggan, Kevin; Klim, Joseph; Williams, Luis; Davis-Dusenbery, Brandi N; Mordes, Daniel; Steinbaugh, Michael; Gamage, Kanchana; Moccia, Rob; Cassel, Seth; Wainger, Brian; Woolf, Clifford (Springer Nature, 2019-01-14)
      The discovery that TDP-43 mutations cause familial ALS and that many patients display pathological TDP-43 mislocalization has nominated altered RNA metabolism as a potential disease mechanism. Despite its importance, the ...

    • Glioblastoma Mimicking an Arteriovenous Malformation 

      Khanna, Arjun; Venteicher, Andrew S.; Walcott, Brian P.; Kahle, Kristopher T.; Mordes, Daniel A.; William, Christopher M.; Ghogawala, Zoher; Ogilvy, Christopher S. (Frontiers Media S.A., 2013)
      Abnormal cerebral vasculature can be a manifestation of a vascular malformation or a neoplastic process. We report the case of a patient with angiography-negative subarachnoid hemorrhage (SAH) who re-presented 3 years later ...

    • Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening 

      Wood, Levi B.; Winslow, Ashley R.; Proctor, Elizabeth A.; McGuone, Declan; Mordes, Daniel A.; Frosch, Matthew P.; Hyman, Bradley T.; Lauffenburger, Douglas A.; Haigis, Kevin M. (Nature Publishing Group, 2015)
      Alzheimer’s disease (AD) therapeutics based on the amyloid hypothesis have shown minimal efficacy in patients, suggesting that the activity of amyloid beta (Aβ) represents only one aspect of AD pathogenesis. Since ...

    • Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging 

      Tian, Feng; Yang, Wenlong; Mordes, Daniel A.; Wang, Jin-Yuan; Salameh, Johnny S.; Mok, Joanie; Chew, Jeannie; Sharma, Aarti; Leno-Duran, Ester; Suzuki-Uematsu, Satomi; Suzuki, Naoki; Han, Steve S.; Lu, Fa-Ke; Ji, Minbiao; Zhang, Rosanna; Liu, Yue; Strominger, Jack; Shneider, Neil A.; Petrucelli, Leonard; Xie, X. Sunney; Eggan, Kevin (Nature Publishing Group, 2016)
      The study of amyotrophic lateral sclerosis (ALS) and potential interventions would be facilitated if motor axon degeneration could be more readily visualized. Here we demonstrate that stimulated Raman scattering (SRS) ...