Browsing by Author "Garshick, Eric"
Now showing items 1-12 of 12
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Cause-specific mortality in the unionized U.S. trucking industry
Laden, Francine; Hart, Jaime Elizabeth; Smith, Thomas J.; Davis, Mary E.; Garshick, Eric (National Institute of Environmental Health Sciences, 2007)Background: Occupational and population-based studies have related exposure to fine particulate air pollution, and specifically particulate matter from vehicle exhausts, to cardiovascular diseases and lung cancer. Objectives: ... -
Chronic Obstructive Pulmonary Disease Mortality in Diesel-Exposed Railroad Workers
Hart, Jaime Elizabeth; Laden, Francine; Schenker, Marc B.; Garshick, Eric (National Institute of Environmental Health Sciences, 2006)Diesel exhaust is a mixture of combustion gases and ultrafine particles coated with organic compounds. There is concern whether exposure can result in or worsen obstructive airway diseases, but there is only limited ... -
Cox Model Setup: Garshick et al. Respond
Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Davis, Mary Elizabeth; Eisen, Ellen A.; Smith, Thomas J. (National Institute of Environmental Health Sciences, 2012) -
A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms
Laden, Francine; Chiu, Yueh-Hsiu; Garshick, Eric; Hammond, S Katharine; Hart, Jaime Elizabeth (BioMed Central, 2013)Background: Previous studies have suggested associations of adult exposures to secondhand smoke (SHS) with respiratory symptoms, but no study has focused on blue-collar industrial environments. We assessed the association ... -
Daily Step Count Predicts Acute Exacerbations in a US Cohort with COPD
Moy, Marilyn Lilun; Teylan, Merilee Ann; Weston, Nicole A.; Gagnon, David R.; Garshick, Eric (Public Library of Science, 2013)Background: COPD is characterized by variability in exercise capacity and physical activity (PA), and acute exacerbations (AEs). Little is known about the relationship between daily step count, a direct measure of PA, and ... -
Exposure-Response Estimates for Diesel Engine Exhaust and Lung Cancer Mortality Based on Data from Three Occupational Cohorts
Vermeulen, Roel; Silverman, Debra T.; Garshick, Eric; Vlaanderen, Jelle; Portengen, Lützen; Steenland, Kyle (National Institute of Environmental Health Sciences, 2013)Background: Diesel engine exhaust (DEE) has recently been classified as a known human carcinogen. Objective: We derived a meta-exposure–response curve (ERC) for DEE and lung cancer mortality and estimated lifetime excess ... -
Gene expression network analyses in response to air pollution exposures in the trucking industry
Chu, Jen-hwa; Hart, Jaime E.; Chhabra, Divya; Garshick, Eric; Raby, Benjamin A.; Laden, Francine (BioMed Central, 2016)Background: Exposure to air pollution, including traffic-related pollutants, has been associated with a variety of adverse health outcomes, including increased cardiopulmonary morbidity and mortality, and increased lung ... -
Lung Cancer and Elemental Carbon Exposure in Trucking Industry Workers
Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Davis, Mary Elizabeth; Eisen, Ellen A.; Smith, Thomas J. (National Institute of Environmental Health Sciences, 2012)Background: Diesel exhaust has been considered to be a probable lung carcinogen based on studies of occupationally exposed workers. Efforts to define lung cancer risk in these studies have been limited in part by lack of ... -
Lung Cancer and Vehicle Exhaust in Trucking Industry Workers
Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Rosner, Bernard Alfred; David, Mary E.; Eisen, Ellen A.; Smith, Thomas J. (National Institute of Environmental Health Sciences, 2008)Background: An elevated risk of lung cancer in truck drivers has been attributed to diesel exhaust exposure. Interpretation of these studies specifically implicating diesel exhaust as a carcinogen has been limited because ... -
Lung Cancer in Railroad Workers Exposed to Diesel Exhaust
Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Rosner, Bernard Alfred; Smith, Thomas J.; Dockery, Douglas W.; Speizer, Frank Erwin (National Institue of Environmental Health Sciences, 2004)Diesel exhaust has been suspected to be a lung carcinogen. The assessment of this lung cancer risk has been limited by lack of studies of exposed workers followed for many years. In this study, we assessed lung cancer ... -
Study design and rationale for investigating phosphodiesterase type 5 inhibition for the treatment of pulmonary hypertension due to chronic obstructive lung disease: the TADA-PHiLD (TADAlafil for Pulmonary Hypertension associated with chronic obstructive Lung Disease) trial
Maron, Bradley A.; Goldstein, Ronald H.; Rounds, Sharon I.; Shapiro, Shelley; Jankowich, Matthew; Garshick, Eric; Moy, Marilyn L.; Gagnon, David; Choudhary, Gaurav (University of Chicago Press, 2013)Abstract In patients with chronic obstructive pulmonary disease (COPD), moderate or severe pulmonary hypertension (COPD-PH) is associated with increased rates of morbidity and mortality. Despite this, approaches to treatment ... -
Traffic-related exposures and biomarkers of systemic inflammation, endothelial activation and oxidative stress: a panel study in the US trucking industry
Neophytou, Andreas M; Hart, Jaime E; Cavallari, Jennifer M; Smith, Thomas J; Dockery, Douglas W; Coull, Brent A; Garshick, Eric; Laden, Francine (BioMed Central, 2013)Background: Experimental evidence suggests that inhaled particles from vehicle exhaust have systemic effects on inflammation, endothelial activation and oxidative stress. In the present study we assess the relationships ...