Browsing by Author "Schatton, Tobias"

Now showing items 1-3 of 3

    • Merkel Cell Carcinoma Expresses Vasculogenic Mimicry: Demonstration in Patients and Experimental Manipulation in Xenografts 

      Lezcano, Cecilia; Kleffel, Sonja; Lee, Nayoung; Larson, Allison R.; Zhan, Qian; DoRosario, Andrew; Wang, Linda C.; Schatton, Tobias; Murphy, George F. (2014)
      Merkel cell carcinoma (MCC) is a highly virulent cutaneous neoplasm that, like melanoma, is a frequent cause of patient morbidity and mortality. The cellular mechanisms responsible for the aggressive behavior of MCC remain ...

    • Nestin depletion induces melanoma matrix metalloproteinases and invasion 

      Lee, Chung-Wei; Zhan, Qian; Lezcano, Cecilia; Frank, Markus H.; Huang, John; Larson, Allison; Lin, Jennifer Y.; Wan, Marilyn T.; Lin, Ping-I; Ma, Jie; Kleffel, Sonja; Schatton, Tobias; Lian, Christine G.; Murphy, George F. (2015)
      Matrix metalloproteinases (MMPs) are key biological mediators of processes as diverse as wound healing, embryogenesis, and cancer progression. Although MMPs may be induced through multiple signaling pathways, the precise ...

    • T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy 

      Sackstein, Robert; Schatton, Tobias; Barthel, Steven (Springer Science and Business Media LLC, 2017-03-27)
      Advances in cancer immunotherapy have offered new hope for patients with metastatic disease. This unfolding success story has been exemplified by a growing arsenal of novel immunotherapeutics, including blocking antibodies ...