Browsing by Author "Croce, Kevin"
Now showing items 1-9 of 9
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Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques
Okamoto, Yoshihisa; Ishii, So; Croce, Kevin James; Katsumata, Harumi; Fukushima, Makoto; Kihara, Shinji; Libby, Peter; Minami, Shiro (Elsevier BV, 2013)Objective Adiponectin (APN) is an adipocytokine with anti-atherogenic and anti-inflammatory properties. Hypoadiponectinemia may associate with increased risk for coronary artery disease (CAD) and acute coronary syndrome ... -
Efficacy of cilostazol on platelet reactivity and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: insights from a meta-analysis of randomised trials
Bangalore, Sripal; Singh, Amita; Toklu, Bora; DiNicolantonio, James J; Croce, Kevin; Feit, Frederick; Bhatt, Deepak L (BMJ Publishing Group, 2014)Background: Cilostazol overcomes high on-treatment platelet reactivity (HTPR) and reduces adverse cardiovascular (CV) outcomes after percutaneous coronary intervention (PCI). However, the role for triple antiplatelet therapy ... -
Endothelial, platelet, and macrophage microparticle levels do not change acutely following transcatheter aortic valve replacement
Marchini, Julio F.; Miyakawa, Ayumi Aurea; Tarasoutchi, Flavio; Krieger, José Eduardo; Lemos, Pedro; Croce, Kevin (BioMed Central, 2016)Background: Patients with severe aortic stenosis have increased levels of prothrombotic and proinflammatory microparticles (MP), and MPs actively regulate pathological processes that lead to atherothrombotic cardiovascular ... -
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis
Miao, Ji; Ling, Alisha V.; Manthena, Praveen V.; Gearing, Mary E.; Graham, Mark J.; Crooke, Rosanne M.; Croce, Kevin J.; Esquejo, Ryan M.; Clish, Clary B.; Torrecilla, Esther; Vázquez, Gumersindo Fernández; Rubio, Miguel A.; Cabrerizo, Lucio; Barabash, Ana; Pernaute, Andrés Sánchez; Torres, Antonio J.; Vicent, David; Biddinger, Sudha B. (Nature Pub. Group, 2015)Despite the well-documented association between insulin resistance and cardiovascular disease, the key targets of insulin relevant to the development of cardiovascular disease are not known. Here, using non-biased profiling ... -
Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in MiceNovelty and Significance
Franck, Grégory; Mawson, Thomas L.; Sausen, Grasiele; Salinas, Manuel; Masson, Gustavo Santos; Cole, Andrew James; Beltrami-Moreira, Marina; Chatzizisis, Yiannis; Quillard, Thibault; Tesmenitsky, Yevgenia; Shvartz, Eugenia; Sukhova, Galina K.; Swirski, Filip K.; Nahrendorf, Matthias; Aikawa, Elena; Croce, Kevin James; Libby, Peter (Ovid Technologies (Wolters Kluwer Health), 2017) -
Monocyte Subset Dynamics in Human Atherosclerosis Can Be Profiled with Magnetic Nano-Sensors
Wildgruber, Moritz; Chudnovskiy, Aleksey; Yoon, Tae-Jong; Etzrodt, Martin; Lee, Hakho; Pittet, Mikael J.; Nahrendorf, Matthias; Croce, Kevin James; Libby, Peter; Weissleder, Ralph; Swirski, Filip K. (Public Library of Science, 2009)Monocytes are circulating macrophage and dendritic cell precursors that populate healthy and diseased tissue. In humans, monocytes consist of at least two subsets whose proportions in the blood fluctuate in response to ... -
Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Theraphy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial
Morrow, David Andrew; Wang, Yunmei; Croce, Kevin James; Sakuma, Masashi; Sabatine, Marc Steven; Gao, Huiyun; Pradhan, Aruna Das; Healy, Aileen M.; Buros, Jacki; McCabe, Carolyn; Libby, Peter; Cannon, Christopher Paul; Braunwald, Eugene; Simon, Daniel I. (Elsevier BV, 2008)Background Using a transcriptional profiling approach, we recently identified myeloid-related protein 8/14 (MRP-8/14) to be expressed by platelets during acute myocardial infarction (MI). Elevated concentrations of MRP-8/14 ... -
Selective Inhibition of Matrix Metalloproteinase-13 Increases Collagen Content of Established Mouse Atherosclerosis
Quillard, T.; Tesmenitsky, Y.; Croce, Kevin James; Travers, R.; Shvartz, E.; Koskinas, K. C.; Sukhova, Galina K.; Aikawa, Elena; Aikawa, Masanori; Libby, Peter (Ovid Technologies (Wolters Kluwer Health), 2011)Objective—Evidence has linked collagen loss with the onset of acute coronary events. This study tested the hypothesis that selective matrix metalloproteinase-13 (MMP-13) collagenase inhibition increases collagen content ... -
Statins Suppress Apolipoprotein CIII-Induced Vascular Endothelial Cell Activation and Monocyte Adhesion
Zheng, Chunyu; Azcutia, Veronica; Aikawa, Elena; Figueiredo, Jose-Luiz; Croce, Kevin James; Sonoki, Hiroyuki; Sacks, Frank Martin; Luscinskas, Francis William; Aikawa, Masanori (Oxford University Press, 2012)Aims: Activation of vascular endothelial cells (ECs) contributes importantly to inflammation and atherogenesis. We previously reported that apolipoprotein CIII (apoCIII), found abundantly on circulating triglyceride-rich ...