Now showing items 1-2 of 2

    • Bright and Fast Multicoloured Voltage Reporters via Electrochromic FRET 

      Zou, Peng; Zhao, Yongxin; Douglass, Adam D.; Hochbaum, Daniel Ron; Brinks, Daan; Werley, Christopher A; Harrison, D. Jed; Campbell, Robert E.; Cohen, Adam Ezra (Nature Publishing Group, 2014)
      Genetically encoded fluorescent reporters of membrane potential promise to reveal aspects of neural function not detectable by other means. We present a palette of multicoloured brightly fluorescent genetically encoded ...
    • Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin 

      Venkatachalam, Veena; Brinks, Daan; Maclaurin, Dougal; Hochbaum, Daniel; Kralj, Joel; Cohen, Adam E. (American Chemical Society, 2014)
      We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin ...