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    • Inhibition of Bacterial Conjugation by Phage M13 and Its Protein g3p: Quantitative Analysis and Model 

      Lin, Abraham; Derr, Julien; Villanueva, Laura; Webber, Mark Alexander; Jimenez, Jose Ignacio; Vera, Pedro; Manapat, Michael; Esvelt, Kevin Michael; Liu, David Ruchien; Chen, Irene Ann (Public Library of Science, 2011)
      Conjugation is the main mode of horizontal gene transfer that spreads antibiotic resistance among bacteria. Strategies for inhibiting conjugation may be useful for preserving the effectiveness of antibiotics and preventing ...
    • Prebiotically Plausible Mechanisms Increase Compositional Diversity Of Nucleic Acid Sequences 

      Derr, Julien; Manapat, Michael L.; Rajamani, Sudha; Leu, Kevin; Xulvi-Brunet, Ramon; Joseph, Isaac; Nowak, Martin A.; Chen, Irene Ann (Oxford University Press, 2012)
      During the origin of life, the biological information of nucleic acid polymers must have increased to encode functional molecules (the RNA world). Ribozymes tend to be compositionally unbiased, as is the vast majority of ...