Browsing Faculty of Arts and Sciences by Author "Dewar, James M."

Now showing items 1-1 of 1

    • DNA interstrand cross-link repair requires replication fork convergence 

      Zhang, Jieqiong; Dewar, James M.; Budzowska, Magda; Motnenko, Anna; Cohn, Martin A.; Walter, Johannes C. (2014)
      DNA interstrand cross-links (ICLs) prevent strand separation during DNA replication and transcription and are therefore extremely cytotoxic. In metazoans, a major pathway of ICL repair is coupled to DNA replication and ...