Browsing Faculty of Arts and Sciences by Author "Dunker, A Keith"

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    • Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms 

      Yang, Jack Y; Dunker, A Keith; Liu, Jun S; Qin, Xiang; Arabnia, Hamid R; Yang, William; Niemierko, Andrzej; Chen, Zhongxue; Luo, Zuojie; Wang, Liangjiang; Liu, Yunlong; Xu, Dong; Deng, Youping; Tong, Weida; Yang, Mary Qu (BioMed Central, 2014)
      Advances of high-throughput technologies have rapidly produced more and more data from DNAs and RNAs to proteins, especially large volumes of genome-scale data. However, connection of the genomic information to cellular ...

    • The emerging genomics and systems biology research lead to systems genomics studies 

      Yang, Mary Qu; Yoshigoe, Kenji; Yang, William; Tong, Weida; Qin, Xiang; Dunker, A Keith; Chen, Zhongxue; Arbania, Hamid R; Liu, Jun S; Niemierko, Andrzej; Yang, Jack Y (BioMed Central, 2014)
      Synergistically integrating multi-layer genomic data at systems level not only can lead to deeper insights into the molecular mechanisms related to disease initiation and progression, but also can guide pathway-based ...

    • Identification of genes and pathways involved in kidney renal clear cell carcinoma 

      Yang, William; Yoshigoe, Kenji; Qin, Xiang; Liu, Jun S; Yang, Jack Y; Niemierko, Andrzej; Deng, Youping; Liu, Yunlong; Dunker, A Keith; Chen, Zhongxue; Wang, Liangjiang; Xu, Dong; Arabnia, Hamid R; Tong, Weida; Yang, Mary Qu (BioMed Central, 2014)
      Background: Kidney Renal Clear Cell Carcinoma (KIRC) is one of fatal genitourinary diseases and accounts for most malignant kidney tumours. KIRC has been shown resistance to radiotherapy and chemotherapy. Like many types ...