Browsing Faculty of Arts and Sciences by Keyword "electron microscopy"

Now showing items 1-7 of 7

    • Atom-by-atom nucleation and growth of graphene nanopores 

      Russo, Craig Anthony; Golovchenko, Jene Andrew (Proceedings of the National Academy of Sciences, 2012)
      Graphene is an ideal thin membrane substrate for creating molecule-scale devices. Here we demonstrate a scalable method for creating extremely small structures in graphene with atomic precision. It consists of inducing ...

    • Biochemical and Structural Studies of Membrane Proteins 

      Wang, Ruiqi Rachel (2012-08-10)
      Membrane proteins live at the interface between a cell and its environment; hence, they play a variety of important physiological roles such as transmembrane transport, signal transduction, and cell adhesion. The importance ...

    • Crowdsourcing the creation of image segmentation algorithms for connectomics 

      Arganda-Carreras, Ignacio; Turaga, Srinivas C.; Berger, Daniel R.; Cireşan, Dan; Giusti, Alessandro; Gambardella, Luca M.; Schmidhuber, Jürgen; Laptev, Dmitry; Dwivedi, Sarvesh; Buhmann, Joachim M.; Liu, Ting; Seyedhosseini, Mojtaba; Tasdizen, Tolga; Kamentsky, Lee; Burget, Radim; Uher, Vaclav; Tan, Xiao; Sun, Changming; Pham, Tuan D.; Bas, Erhan; Uzunbas, Mustafa G.; Cardona, Albert; Schindelin, Johannes; Seung, H. Sebastian (Frontiers Media S.A., 2015)
      To stimulate progress in automating the reconstruction of neural circuits, we organized the first international challenge on 2D segmentation of electron microscopic (EM) images of the brain. Participants submitted boundary ...

    • Molecular and cellular mechanisms underlying adult blood-brain barrier maintenance 

      du Maine, Xavier J (2022-01-20)
      To ensure optimal neuronal function, the blood-brain barrier (BBB) maintains a homeostatic brain microenvironment free from harmful agents and delivers nutrients to the brain to support metabolic needs. Although the BBB ...

    • The Structure of Motor Control Circuits in Adult Drosophila 

      Phelps, Jasper Selvin (2021-05-10)
      Animals’ nervous systems are able to coordinate contractions of dozens of muscles to smoothly navigate complex environments. Engineering animal-level mobility into robots is a major goal of current robotics research, but ...

    • Ultrastructural insights into mammalian cutaneous mechanoreceptors 

      Zhang, Qiyu (2021-05-07)
      Cutaneous mechanoreceptors are a morphologically and functionally diverse class of primary sensory neurons in mammals that transduce mechanical stimuli acting on the skin into electrical impulses. These neurons reside in ...

    • Validation of the Orthogonal Tilt Reconstruction Method with a Biological Test Sample 

      Chandramouli, Preethi; Hernandez-Lopez, Rogelio Antonio; Wang, Hong-Wei; Leschziner, Andres (Elsevier, 2011)
      Electron microscopy of frozen-hydrated samples (cryo-EM) can yield high resolution structures of macromolecular complexes by accurately determining the orientation of large numbers of experimental views of the sample ...