Browsing Faculty of Arts and Sciences by Keyword "inhibition"

Now showing items 1-7 of 7

    • Dissecting Olfactory Circuits in Drosophila 

      Liu, Wendy Wing-Heng (2014-06-06)
      Drosophila is a simple and genetically tractable model system for studying neural circuits. This dissertation consists of two studies, with the broad goal of understanding sensory processing in neural circuits using ...

    • Distinct Spatiotemporal Activity in Principal Neurons of the Mouse Olfactory Bulb in Anesthetized and Awake States 

      Blauvelt, David Gregory; Sato, Tomokazu F.; Wienisch, Martin; Murthy, Venkatesh N. (Frontiers Media S.A., 2013)
      The acquisition of olfactory information and its early processing in mammals are modulated by brain states through sniffing behavior and neural feedback. We imaged the spatiotemporal pattern of odor-evoked activity in a ...

    • Functional Development and Plasticity of Parvalbumin Cells in Visual Cortex: Role of Thalamocortical Input 

      Quast, Kathleen Beth (2013-03-15)
      Unlike principal excitatory neurons, cortical interneurons comprise a diverse group of distinct subtypes. They can be classified by their morphology, molecular content, developmental origins, electrophysiological properties ...

    • High-Affinity Alkynyl Bisubstrate Inhibitors of NicotinamideN-Methyltransferase (NNMT) 

      Policarpo, Rocco; Decultot, Ludovic; May, Elizabeth; Kuzmič, Petr; Carlson, Samuel; Huang, Danny; Chu, Vincent; Wright, Brandon; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo; Rani, Shilpa; Dittakavi, Sreekanth; Panarese, Joseph; Gaudet, Rachelle; Shair, Matthew (American Chemical Society (ACS), 2019-10-07)
      Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that methylates nicotinamide (NAM) using cofactor S-adenosylmethionine (SAM). NNMT overexpression has been linked to diabetes, obesity, and various cancers. In ...

    • Inhibition of Action, Thought, and Emotion: A Selective Neurobiological Review 

      Dillon, Daniel; Pizzagalli, Diego (Elsevier, 2007)
      The neural bases of inhibitory function are reviewed, covering data from paradigms assessing inhibition of motor responses (antisaccade, go/nogo, stop-signal), cognitive sets (e.g., Wisconsin Card Sort Test), and emotion ...

    • Inhibition of Pectin Methyl Esterase Activity By Green Tea Catechins 

      Lewis, Kristin; Selzer, Tzvia; Shahar, Chen; Tworowski, Dmitry; Sagi, Irit (Elsevier, 2008)
      Pectin methyl esterases (PMEs) and their endogenous inhibitors are involved in the regulation of many processes in plant physiology, ranging from tissue growth and fruit ripening to parasitic plant haustorial formation and ...

    • Inhibition of the βbarrel assembly machine by a peptide that binds BamD 

      Hagan, Christine Lepicier; Wzorek, Joseph Stanley; Kahne, Daniel (Proceedings of the National Academy of Sciences, 2015)
      The protein complex that assembles integral membrane β-barrel proteins in the outer membranes of Gram-negative bacteria is an attractive target in the development of new antibiotics. This complex, the β-barrel assembly ...